The Metaverse, an expanding digital space, is at the forefront of a technological revolution that will redefine how we interact with the digital world. Yet, as this fascinating landscape evolves, it presents an array of complex challenges, particularly in the realm of entrepreneurship. The current literature on Metaverse entrepreneurship is notably lacking, leaving a void in our understanding of the Metaverse's potential and the role of entrepreneurs within it. Critical questions about the emergence of entrepreneurial ecosystems, the evolution of entrepreneurship frontiers, and the impact of innovation and creativity within the Metaverse remain largely unanswered. Entrepreneurship and Creativity in the Metaverse serves as a guide to comprehending and harnessing the Metaverse's vast potential. As a space with fewer limitations than the physical world, creativity and entrepreneurship have immense potential to flourish within the Metaverse. It provides a much-needed roadmap for scholars, entrepreneurs, educators, industry experts, and policymakers to navigate this uncharted territory and thrive within it.